الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>7-O-(Amino-PEG4)-paclitaxel

7-O-(Amino-PEG4)-paclitaxel

رقم الكتالوجGC60033

7-O- (Amino-PEG4) -paclitaxel هو رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs

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7-O-(Amino-PEG4)-paclitaxel التركيب الكيميائي

الحجم السعر المخزون الكميّة
10mg
501٫00
متوفر
25mg
899٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

7-O-(Amino-PEG4)-paclitaxel is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

مراجعات

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Review for 7-O-(Amino-PEG4)-paclitaxel

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