ALK2-IN-2 |
| رقم الكتالوجGC65294 |
ALK2-IN-2 هو مثبط قوي وانتقائي للكيناز 2 الشبيه بمستقبلات أكتيفين (ALK2) مع IC50 من 9 نانومتر ، وانتقائية أكثر من 700 ضعف ضد ALK3
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2254409-25-9
Sample solution is provided at 25 µL, 10mM.
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ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].
[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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