Boldine (Synonyms: (+)-(S)-Boldine, 2,9-Dihydroxy-1,10-dimethoxyaporphine, NSC 65689) |
| رقم الكتالوجGC40876 |
بولدين هو قلويد أبورفين أيزوكينولين مستخلص من جذر ليتسي كوبيبا ويمتلك أيضًا هذه الخصائص ، بما في ذلك التأثيرات المضادة للأكسدة والمضادة للالتهابات والحماية الخلوية
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Cas No.: 476-70-0
Sample solution is provided at 25 µL, 10mM.
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Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1].
References:
[1]. Zhao H , et al. Boldine isolated from Litsea cubeba inhibits bone resorption by suppressing the osteoclast differentiation in collagen-induced arthritis. Int Immunopharmacol. 2017 Oct;51:114-123.
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