Boldine (Synonyms: (+)-(S)-Boldine, 2,9-Dihydroxy-1,10-dimethoxyaporphine, NSC 65689) |
| Catalog No.GC40876 |
La boldine est un alcaloÏde aporphine isoquinoline extrait de la racine de Litsea cubeba et possède également ces propriétés, notamment des effets antioxydants, anti-inflammatoires et cytoprotecteurs.
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Cas No.: 476-70-0
Sample solution is provided at 25 µL, 10mM.
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Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1].
References:
[1]. Zhao H , et al. Boldine isolated from Litsea cubeba inhibits bone resorption by suppressing the osteoclast differentiation in collagen-induced arthritis. Int Immunopharmacol. 2017 Oct;51:114-123.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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