BTR-1 |
| رقم الكتالوجGC34511 |
BTR-1 هو عامل نشط مضاد للسرطان ، ويسبب توقف طور S ، ويؤثر على تكرار الحمض النووي في خلايا سرطان الدم. ينشط BTR-1 موت الخلايا المبرمج ويحث على موت الخلايا.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18331-34-5
Sample solution is provided at 25 µL, 10mM.
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BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death[1]. Apoptosis[1]
BTR-1 (10, 50, 100, and 250 µM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 µM at 48 and 72 h, respectively[1]. Cell Viability Assay[1] Cell Line: T-cell leukemic cell lines
[1]. Moorthy BT, et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6297-301.
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