Enbezotinib |
| رقم الكتالوجGC65354 |
يمكن أن يثبط Enbezotinib ، وهو مثبط لـ RET ، الفسفرة الذاتية RETيمكن استخدام Enbezotinib لأبحاث السرطان
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Cas No.: 2359649-81-1
Sample solution is provided at 25 µL, 10mM.
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Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1].
Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1].
Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1].
[1]. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.
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