Enbezotinib |
| Catalog No.GC65354 |
L'enbezotinib, un inhibiteur de RET, peut inhiber l'autophosphorylation de RET. L'enbezotinib peut être utilisé pour la recherche sur le cancer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2359649-81-1
Sample solution is provided at 25 µL, 10mM.
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Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1].
Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1].
Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1].
[1]. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.
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