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Enbezotinib

Catalog No.GC65354

Enbezotinib, un inhibidor de RET, puede inhibir la autofosforilaciÓn de RET. Enbezotinib se puede utilizar para la investigaciÓn del cÁncer.

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Enbezotinib Chemical Structure

Cas No.: 2359649-81-1

Tamaño Precio Disponibilidad Cantidad
5mg
405,00 $
Disponible
10mg
630,00 $
Disponible
25mg
1.332,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1].

Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1].

Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1].

[1]. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.

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