الصفحة الرئيسية>>Signaling Pathways>> Tyrosine Kinase>> c-FMS>>c-Fms-IN-8

c-Fms-IN-8

رقم الكتالوجGC35665

c-Fms-IN-8 (المركب 4 أ) هو عامل تحفيز للمستعمرة -1 (CSF-1R ، c-FMS) مثبط من النوع الثاني ، مع IC50 من 9.1 نانومتر

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c-Fms-IN-8 التركيب الكيميائي

Cas No.: 1255303-58-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1]. IC50: 9.1 nM (CSF-1R)[1].

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

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