DMT1 blocker 2 |
| رقم الكتالوجGC35886 |
يعتبر مانع DMT1 2 مثبطًا مباشرًا لناقل المعادن ثنائي التكافؤ 1 (DMT1) ، مع IC50 بمقدار 0.83 ميكرومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1062648-63-8
Sample solution is provided at 25 µL, 10mM.
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DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].
IC50: 0.83 μM (DMT1 blocker 2)[1]
[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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