Thalidomide-O-amido-C3-NH2 (TFA) (Synonyms: Cereblon Ligand-Linker Conjugates 16 TFA; E3 Ligase Ligand-Linker Conjugates 52 TFA) |
| رقم الكتالوجGC38095 |
ثاليدوميد- O-amido-C3-NH2 (TFA) عبارة عن اتحاد مركب E3 ligase ligand-linker مُصنَّع يشتمل على يجند cereblon القائم على ثاليدومايد ورابط مستخدم في تقنية PROTAC.
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Cas No.: 2022182-58-5
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.
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