RU-301 |
| رقم الكتالوجGC38580 |
RU-301 هو أحد مثبطات TAM الذي يمنع تنشيط TAM الناجم عن الغاز6 وتكوين الأورام
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Cas No.: 1110873-99-8
Sample solution is provided at 25 µL, 10mM.
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RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].
[1]. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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