Lenalidomide-PEG1-azide |
| رقم الكتالوجGC64867 |
Lenalidomide-PEG1-azide عبارة عن اتحاد E3 ligase lgand-linkerيشتمل Lenalidomide-PEG1-azide على يجند cereblon القائم على Lenalidomide ورابطيمكن استخدام Lenalidomide-PEG1-azide لتصميم PROTAC BRD4 Degrader-2
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Cas No.: 2185795-67-7
Sample solution is provided at 25 µL, 10mM.
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Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 [1].
[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
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