Lenalidomide-PEG1-azide |
| カタログ番号GC64867 |
レナリドマイド-PEG1-アジドは、E3リガーゼリガンド-リンカーコンジュゲートです。レナリドマイド-PEG1-アジドには、レナリドマイドベースのセレブロンリガンドとリンカーが組み込まれています。レナリドマイド-PEG1-アジド は、PROTAC BRD4 Degrader-2 の設計に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2185795-67-7
Sample solution is provided at 25 µL, 10mM.
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Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 [1].
[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
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