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Lenalidomide-PEG1-azide

Catalog No.GC64867

Lenalidomida-PEG1-azida es un conjugado ligasa-enlazador E3. Lenalidomide-PEG1-azide incorpora el ligando de cereblon basado en lenalidomida y un enlazador. Lenalidomida-PEG1-azida se puede utilizar para diseÑar un PROTAC BRD4 Degrader-2.

Products are for research use only. Not for human use. We do not sell to patients.

Lenalidomide-PEG1-azide Chemical Structure

Cas No.: 2185795-67-7

Tamaño Precio Disponibilidad Cantidad
50 mg
675,00 $
Disponible
100 mg
1.080,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 [1].

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

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