Metaproterenol (hemisulfate) (Synonyms: dl-Metaproterenol, dl-Orciprenaline) |
رقم الكتالوجGC44169 |
Metaproterenol (hemisulfate) (Orciprenaline hemisulfate) هو مقلد للودي مباشر المفعول ومحفز لمستقبلات β2 الأدرينالية (β2AR) مع IC50 من 68 نانومتر.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5874-97-5
Sample solution is provided at 25 µL, 10mM.
Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions. It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol . Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively). Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
Average Rating: 5
(Based on Reviews and 25 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *