Norleual |
رقم الكتالوجGC50152 |
Norleual ، أنجيوتنسين (Ang) IV ، هو عامل نمو خلايا الكبد (HGF) / مثبط c-Met مع IC 50 من 3 مساءً
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Cas No.: 334994-34-2
Sample solution is provided at 25 µL, 10mM.
Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic.
Yamamoto et al (2010) The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor. J.Pharmacol.Exp.Ther. 333 161 PMID:20086056
Average Rating: 5
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