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NT219

رقم الكتالوجGC69599 Copy One-Click Copy Product Info

NT219 هو مثبط مزدوج فعال لمستقبل الأنسولين 1/2 (IRS1/2) و STAT3. يعتبر IRS1/2 و STAT3 روابط إشارة رئيسية تحت تنظيم عدة جينات سرطانية. يؤثر NT219 على تحلل IRS1/2 ويثبط تفاعل STAT3 بالفسفرة. يتمتع NT219 بإمكانية دراسة أمراض السرطان.

Products are for research use only. Not for human use. We do not sell to patients.

NT219 التركيب الكيميائي

Cas No.: 1198078-60-2

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
269٫00
متوفر
1mg
135٫00
متوفر
5mg
297٫00
متوفر
10mg
432٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Chemical Properties of NT219

Cas No. 1198078-60-2 SDF
Formula C16H14BrNO5S M.Wt 412.26
الذوبان DMSO : ≥ 100 mg/mL (242.57 mM) Storage Store at -20°C, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of NT219

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4257 mL 12.1283 mL 24.2565 mL
5 mM 485.1 μL 2.4257 mL 4.8513 mL
10 mM 242.6 μL 1.2128 mL 2.4257 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

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In vivo Formulation Calculator (Clear solution) of NT219

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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مراجعات

Review for NT219

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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