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NT219

Catalog No.GC69599 Copy One-Click Copy Product Info

NT219 es un inhibidor doblemente efectivo de sustratos del receptor de insulina 1/2 (IRS1/2) y STAT3. IRS1/2 y STAT3 son las principales conexiones de señal reguladas por varios oncogenes. NT219 afecta la degradación de IRS1/2 e inhibe la fosforilación de STAT3. NT219 tiene el potencial para investigar enfermedades cancerosas.

Products are for research use only. Not for human use. We do not sell to patients.

NT219 Chemical Structure

Cas No.: 1198078-60-2

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
269,00 $
Disponible
1mg
135,00 $
Disponible
5mg
297,00 $
Disponible
10mg
432,00 $
Disponible

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Chemical Properties of NT219

Cas No. 1198078-60-2 SDF
Formula C16H14BrNO5S M.Wt 412.26
Solubility DMSO : ≥ 100 mg/mL (242.57 mM) Storage Store at -20°C, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of NT219

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4257 mL 12.1283 mL 24.2565 mL
5 mM 485.1 μL 2.4257 mL 4.8513 mL
10 mM 242.6 μL 1.2128 mL 2.4257 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of NT219

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for NT219

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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