PX20606 trans racemate (PX-102 trans racemate) |
| رقم الكتالوجGC31395 |
PX20606 عبر زملاء السباق (PX-102 transemate) (PX-102 transemate) هو ناهض FXR مع EC50s من 32 و 34 نانومتر لـ FXR في اختبار FRET و M1H ، على التوالي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1268244-85-4
Sample solution is provided at 25 µL, 10mM.
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PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.
[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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