PX20606 trans racemate (PX-102 trans racemate) |
| Catalog No.GC31395 |
Le racémate trans PX20606 (racémate trans PX-102) (racémate trans PX-102) est un agoniste de FXR avec des CE50 de 32 et 34 nM pour FXR dans les tests FRET et M1H, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1268244-85-4
Sample solution is provided at 25 µL, 10mM.
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PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.
[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.
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