(Rac)-IDO1-IN-5 |
| رقم الكتالوجGC38876 |
(راك) -IDO1-IN-5 (مثال 1) هو زملاء IDO1-IN-5IDO1-IN-5 هو مثبط قوي وانتقائي ومخترق في الدماغ لنشاط Indoleamine 2،3-Dioxygenase 1 (IDO1) ، ويرتبط بـ apo-IDO1 الذي يفتقر إلى الهيم بدلاً من IDO1 الناضج المرتبط بالهيم
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Cas No.: 2166616-74-4
Sample solution is provided at 25 µL, 10mM.
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(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
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