(Rac)-IDO1-IN-5 |
| Katalog-Nr.GC38876 |
(Rac)-IDO1-IN-5 (Beispiel 1) ist ein Racemat von IDO1-IN-5. IDO1-IN-5 ist ein potenter, selektiver und in das Gehirn eindringender Inhibitor der AktivitÄt von Indolamin 2,3-Dioxygenase 1 (IDO1), der an Apo-IDO1 bindet, dem HÄm fehlt, und nicht an reifes HÄm-gebundenes IDO1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2166616-74-4
Sample solution is provided at 25 µL, 10mM.
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(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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