الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>VH 032, phenol

VH 032, phenol

رقم الكتالوجGC50607

VH 032 ، الفينول هو يجند VHL القائم على VH032. VH 032 ، يمكن توصيل الفينول برباط البروتين بواسطة رابط لتكوين PROTACs.

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VH 032, phenol التركيب الكيميائي

Cas No.: 2244684-42-0

الحجم السعر المخزون الكميّة
50 mg
657٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Maniaci et al (2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat.Comm. 8 830 PMID:29018234

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