Chromatin/Epigenetics
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Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
Research Areas
- Bromodomain(44)
- Aurora Kinase(74)
- DNA Methyltransferase(43)
- HDAC(249)
- Histone Acetyltransferases(98)
- Histone Demethylases(120)
- Histone Methyltransferase(277)
- HIF(127)
- JAK(188)
- PARP(162)
- Pim(35)
- Protein Ser/Thr Phosphatases(23)
- RNA Polymerase(4)
- Sirtuin(87)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(3)
- PAD(20)
- Epigenetic Reader Domain(292)
- MicroRNA(33)
- Protein Arginine Deiminase(17)
- Chromodomain(1)
- Citrullination(20)
- DNA/RNA Demethylation(2)
- DNA/RNA Methylation(8)
- Histone Deacetylation(43)
- Histones/Histone Peptides(62)
- PHD Domains(1)
- Tandem Tudor & Tudor-like Domains(1)
- PRMT(2)
- Readers(1)
- Small Interfering RNA (siRNA)(16)
- METTL3(4)
- WDR5(8)
- TET Protein(2)
- HuR(2)
- SF3B1(2)
Products Related to Chromatin/Epigenetics(1939)
- GC43841Histone H3K27Ac (21-43)-GGK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Ac (21-43)-GGK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-44 of the human histone H3.1 and H3.2 sequences.
- GC43842Histone H3K27Ac (21-44)-GK-biotin amide (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Ac (21-44)-GK-biotin amide is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence.
- GC43843Histone H3K27Ac (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Ac (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.
- GC43844Histone H3K27Me1 (15-39)-K-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me1 (15-39) is a peptide fragment of histone H3 that corresponds to amino acid residues 16-40 of the human histone H3.1 and H3.2 sequences.
- GC43845Histone H3K27Me1 (21-44)-GK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me1 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences.
- GC43846Histone H3K27Me1 (23-34) (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me1 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.
- GC43847Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences.
- GC43848Histone H3K27Me2 (23-34) (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.
- GC43849Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences.
- GC43850Histone H3K27Me3 (21-44)-K-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me3 (21-44)-K-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences.
- GC43851Histone H3K27Me3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K27Me3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.
- GC43852Histone H3K36Me2 (21-44)-GK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K36Me2 (21-44) is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences.
- GC43853Histone H3K36Me3 (21-44)-GK-biotin (trifluoroacetate salt)Purity: >95.00%
Histone H3K36Me3 (21-44) is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences.
- GC43854Histone H3K4Me1 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K4Me1 (1-10) is an N-terminal fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence.
- GC43855Histone H3K4Me1 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K4Me1 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence.
- GC43856Histone H3K4Me2 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K4Me2 (1-10) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence.
- GC43857Histone H3K4Me2 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K4Me2 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence.
- GC43858Histone H3K4Me3 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K4Me3 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence.
- GC43859Histone H3K79Me3 (73-83) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K79Me3 (73-83) is a peptide fragment of histone H3 that corresponds to amino acid residues 74-84 of the human histone H3 sequence.
- GC43860Histone H3K9Ac (1-20) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K9Ac (1-20) is an N-terminal peptide fragment that corresponds to amino acid residues 2-21 of the human histone H3 sequence.
- GC43861Histone H3K9Ac (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K9Ac (1-21) is an N-terminal peptide fragment that corresponds to amino acid residues 2-22 of the human histone H3 sequence.
- GC43862Histone H3K9Me3 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K9Me3 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence.
- GC43863Histone H3K9Me3 (1-24) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)Purity: >95.00%
Histone H3K9Me3 (1-24) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-25 of the human histone H3 sequence.
- GC43864Histone H4 Peptide Substrate (1-21)Purity: >95.00%
Histone H4 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC43841 | Histone H3K27Ac (21-43)-GGK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Ac (21-43)-GGK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-44 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43842 | Histone H3K27Ac (21-44)-GK-biotin amide (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Ac (21-44)-GK-biotin amide is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence. | ||||
| GC43843 | Histone H3K27Ac (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Ac (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43844 | Histone H3K27Me1 (15-39)-K-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me1 (15-39) is a peptide fragment of histone H3 that corresponds to amino acid residues 16-40 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43845 | Histone H3K27Me1 (21-44)-GK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me1 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43846 | Histone H3K27Me1 (23-34) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me1 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43847 | Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. | ||||
| GC43848 | Histone H3K27Me2 (23-34) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43849 | Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. | ||||
| GC43850 | Histone H3K27Me3 (21-44)-K-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me3 (21-44)-K-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43851 | Histone H3K27Me3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K27Me3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43852 | Histone H3K36Me2 (21-44)-GK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K36Me2 (21-44) is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences. | ||||
| GC43853 | Histone H3K36Me3 (21-44)-GK-biotin (trifluoroacetate salt) | - | >95.00% | |
Histone H3K36Me3 (21-44) is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. | ||||
| GC43854 | Histone H3K4Me1 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K4Me1 (1-10) is an N-terminal fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence. | ||||
| GC43855 | Histone H3K4Me1 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K4Me1 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence. | ||||
| GC43856 | Histone H3K4Me2 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K4Me2 (1-10) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence. | ||||
| GC43857 | Histone H3K4Me2 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K4Me2 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence. | ||||
| GC43858 | Histone H3K4Me3 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K4Me3 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence. | ||||
| GC43859 | Histone H3K79Me3 (73-83) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K79Me3 (73-83) is a peptide fragment of histone H3 that corresponds to amino acid residues 74-84 of the human histone H3 sequence. | ||||
| GC43860 | Histone H3K9Ac (1-20) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K9Ac (1-20) is an N-terminal peptide fragment that corresponds to amino acid residues 2-21 of the human histone H3 sequence. | ||||
| GC43861 | Histone H3K9Ac (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K9Ac (1-21) is an N-terminal peptide fragment that corresponds to amino acid residues 2-22 of the human histone H3 sequence. | ||||
| GC43862 | Histone H3K9Me3 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K9Me3 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence. | ||||
| GC43863 | Histone H3K9Me3 (1-24) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) | - | >95.00% | |
Histone H3K9Me3 (1-24) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-25 of the human histone H3 sequence. | ||||
| GC43864 | Histone H4 Peptide Substrate (1-21) | - | >95.00% | |
Histone H4 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. | ||||
