Rupintrivir (Synonyms: AG7088) |
| رقم الكتالوجGC50441 |
Rupintrivirvr (AG7088) ، دواء مضاد للفيروسات ، هو مثبط قوي وانتقائي ولا رجعة فيه لبروتياز فيروس الأنف البشري (HRV) 3C
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 223537-30-2
Sample solution is provided at 25 µL, 10mM.
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Potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). Exhibits no significant inhibition against a variety of serine and cysteine proteases. Inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays. products are for biomedical research use only. They are not intended for human or veterinary use.
Patick et al (1999) In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob.Agents Chemother. 43 2444 PMID:10508022 |Dragovich et al (1999) Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J.Med.Chem. 42 1203 PMID:10197964
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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