Sauristolactam (Saurolactam) (Synonyms: Saurolactam) |
رقم الكتالوجGC31191 |
Sauristolactam (Saurolactam) ، أرستلاكتام طبيعي معزول من الأجزاء الهوائية من Saururus chinensis ، له نشاط عصبي كبير ضد السمية التي يسببها الغلوتامات في الخلايا القشرية الأولية للجرذان المستزرعة.
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Cas No.: 128533-02-8
Sample solution is provided at 25 µL, 10mM.
Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].
[1]. Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6. [2]. Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72(3):719-26.
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