Sauristolactam (Saurolactam) (Synonyms: Saurolactam) |
| カタログ番号GC31191 |
サウリストラクタム (サウロラクタム)、Saururus chinensis の空中部分から分離された天然のアリストラクタムは、初代培養ラット皮質細胞におけるグルタミン酸誘発毒性に対して有意な神経保護活性を持っています。
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Cas No.: 128533-02-8
Sample solution is provided at 25 µL, 10mM.
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Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].
[1]. Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6. [2]. Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72(3):719-26.
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