Solanidine (Synonyms: (–)-Solanidine, 22R,25S-Solanidine, NSC 76025) |
| رقم الكتالوجGC52075 |
Solanidine هو قلويد كولستان معزول من عدة أنواع من البطاطس بما في ذلك Solanum demissum و Solanum acaule و Solanum tuberosum. يمكن أن يمنع Solanidine الانتشار ويظهر تأثير مضاد للأورام واضح.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80-78-4
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Solanidine is a steroidal glycoalkaloid metabolite that has been found in potato (S. tuberosum) and has anticancer and teratogenic activities.1,2,3 It inhibits the growth of HT-29 colon and HepG2 liver cancer cells by 80.9 and 82.2%, respectively, when used at a concentration of 100 μg/ml.2 Solanidine (176 mg/kg) is teratogenic to hamster embryos when administered to pregnant dams on day eight of gestation.3
1.Nikolic, N.C., and Stankovic, M.Z.Solanidine hydrolytic extraction and separation from the potato (Solanum tuberosum L.) vines by using solid-liquid-liquid systemsJ. Agric. Food Chem.51(7)1845-1849(2003) 2.Lee, K.-R., Kozukue, N., Han, J.-S., et al.Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cellsJ. Agric. Food Chem.52(10)2832-2839(2004) 3.Gaffield, W., and Keeler, R.F.Implication of C-5, C-6 unsaturation as a key structural factor in steroidal alkaloid-induced mammalian teratogenesisExperientia49(10)922-924(1993)
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *