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Solanidine (Synonyms: (–)-Solanidine, 22R,25S-Solanidine, NSC 76025)

Catalog No.GC52075

La solanidine est un alcaloÏde du cholestane isolé de plusieurs espèces de pommes de terre, notamment Solanum demissum, Solanum acaule et Solanum tuberosum. La solanidine peut inhiber la prolifération et présenter un effet antitumoral évident.

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Solanidine Chemical Structure

Cas No.: 80-78-4

Taille Prix Stock Qté
1 mg
87,00 $US
En stock
5 mg
324,00 $US
En stock
10 mg
556,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Solanidine is a steroidal glycoalkaloid metabolite that has been found in potato (S. tuberosum) and has anticancer and teratogenic activities.1,2,3 It inhibits the growth of HT-29 colon and HepG2 liver cancer cells by 80.9 and 82.2%, respectively, when used at a concentration of 100 μg/ml.2 Solanidine (176 mg/kg) is teratogenic to hamster embryos when administered to pregnant dams on day eight of gestation.3

1.Nikolic, N.C., and Stankovic, M.Z.Solanidine hydrolytic extraction and separation from the potato (Solanum tuberosum L.) vines by using solid-liquid-liquid systemsJ. Agric. Food Chem.51(7)1845-1849(2003) 2.Lee, K.-R., Kozukue, N., Han, J.-S., et al.Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cellsJ. Agric. Food Chem.52(10)2832-2839(2004) 3.Gaffield, W., and Keeler, R.F.Implication of C-5, C-6 unsaturation as a key structural factor in steroidal alkaloid-induced mammalian teratogenesisExperientia49(10)922-924(1993)

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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