Tpl2 Kinase Inhibitor (Synonyms: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor) |
| رقم الكتالوجGC45067 |
مثبط Tpl2 Kinase (المركب 1) هو مثبط فعال وانتقائي لـ Tpl2 (COT kinase ، MAP3K8) ، يلعب دورًا مهمًا في تنظيم الاستجابة الالتهابية وتطور بعض أنواع السرطان.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 871307-18-5
Sample solution is provided at 25 µL, 10mM.
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Tpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 (Tpl2; pIC50 = 7.3). It blocks LPS-induced TNF-α production in mice and human monocytes. Tpl2 kinase inhibitor has been used to evaluate the role of this enzyme in the proliferation and differentiation of cancer cells.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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