Tpl2 Kinase Inhibitor (Synonyms: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor) |
Catalog No.GC45067 |
Tpl2 Kinase Inhibitor (Compuesto 1) es un potente y selectivo inhibidor de Tpl2 (COT quinasa, MAP3K8), juega un papel importante en la regulaciÓn de la respuesta inflamatoria y la progresiÓn de algunos tipos de cÁncer.
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Cas No.: 871307-18-5
Sample solution is provided at 25 µL, 10mM.
Tpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 (Tpl2; pIC50 = 7.3). It blocks LPS-induced TNF-α production in mice and human monocytes. Tpl2 kinase inhibitor has been used to evaluate the role of this enzyme in the proliferation and differentiation of cancer cells.
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