Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(36)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(52)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(7)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(304)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(22)
- PLK(51)
- PTEN(7)
- Wee1(17)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(78)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
- Mitosis(2)
Products Related to Cell Cycle/Checkpoint(1553)
- GC46347(S)-(+)-MethopreneCAS: 65733-16-6Purity: >95.00%
(S)-Methopren ist ein Juvenilhormon-Analogon, das die Fähigkeit des Insekts verhindert, sich von der Puppe zum Erwachsenen zu verändern, und als Insektizid verwendet wird.
- GC46351(S)-CR8CAS: 1084893-56-0Purity: >98.00%
(S)-CR8 ist das S-Isomer von CR8. (S)-CR8 ist ein potenter und selektiver CDK-Inhibitor mit IC50-Werten von 0,060, 0,080, 0,11, 0,12 und 0,15 μM fÜr CDK2/Cyclin E, CDK2/Cyclin A, CDK9/Cyclin T, CDK5/p25 und CDK1/Cyclin B bzw. (S)-CR8 reduziert das Überleben von SH-SY5Y-Zellen (IC50 0,40 μM).
- GC463791,2-Dioleoyl-sn-glycero-3-PS (sodium salt)CAS: 90693-88-2Purity: >98.00%
1,2-Dioleoyl-sn-glycero-3-PS (Natriumsalz) ist ein Ersatzstoff fÜr Phosphoserin/Phosphatidylserin.
- GC463851,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-MannopyranoseCAS: 68733-20-0Purity: >95.00%
A ManNAc analog and building block
- GC4643413C15-NivalenolCAS: 911392-40-0Purity: >98.00%
An internal standard for the quantification of nivalenol
- GC4644615-deoxy-δ12,14-Prostaglandin J2-biotinPurity: >98.00%
A neuropeptide with diverse biological activities
- GC465823-Acetyldeoxy Nivalenol-13C17CAS: 1217476-81-7Purity: >98.00%
An internal standard for the quantification of 3-acetyldeoxy nivalenol
- GC466064-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)anilineCAS: 214360-73-3Purity: >98.00%
A heterocyclic building block
- GC466354-deoxy Nivalenol-13C15CAS: 911392-36-4Purity: >98.00%
An internal standard for the quantification of 4-deoxy nivalenol
- GC466875'-Deoxy-5'-methylthioadenosine-d3CAS: 174838-38-1Purity: >99.00%
A neuropeptide with diverse biological activities
- GC467337,12-Dimethylbenz[a]anthraceneCAS: 57-97-6Purity: >98.00%
7,12-Dimethylbenz[a]anthracen hat als polyzyklischer aromatischer Kohlenwasserstoff (PAK) krebserzeugende Wirkung. 7,12-Dimethylbenz[a]anthracen wird verwendet, um die Tumorbildung in verschiedenen Nagetiermodellen zu induzieren.
- GC46790Acibenzolar-S-methylCAS: 135158-54-2Purity: >99.00%
A fungicide inducer of systemic acquired resistance
- GC46791Ac-LEHD-pNA (trifluoroacetate salt)Purity: >95.00%
A neuropeptide with diverse biological activities
- GC46796Ac-WEHD-AFC (trifluoroacetate salt)Purity: >95.00%
A neuropeptide with diverse biological activities
- GC46810Aflatoxin B1-13C17CAS: 1217449-45-0Purity: >98.00%
An internal standard for the quantification of aflatoxin B 1
- GC46811Aflatoxin B2-13C17CAS: 1217470-98-8Purity: >98.00%
An internal standard for the quantification of aflatoxin B 2
- GC46814Aflatoxin M1-13C17CAS: 2707441-97-0Purity: >98.00%
A neuropeptide with diverse biological activities
- GC46841Amiloride (hydrochloride) (hydrate)Purity: >98.00%
A neuropeptide with diverse biological activities
- GC46867Apremilast-d5CAS: 1258597-47-5Purity: >99.00%
Apremilast D5 (CC-10004 D5) ist ein Deuterium mit der Bezeichnung Apremilast.
- GC46878AranciamycinCAS: 72389-06-1Purity: >70.00%
A fungal metabolite with diverse biological activities
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC46347 | (S)-(+)-Methoprene | 65733-16-6 | >95.00% | |
(S)-Methopren ist ein Juvenilhormon-Analogon, das die Fähigkeit des Insekts verhindert, sich von der Puppe zum Erwachsenen zu verändern, und als Insektizid verwendet wird. | ||||
| GC46351 | (S)-CR8 | 1084893-56-0 | >98.00% | |
(S)-CR8 ist das S-Isomer von CR8. (S)-CR8 ist ein potenter und selektiver CDK-Inhibitor mit IC50-Werten von 0,060, 0,080, 0,11, 0,12 und 0,15 μM fÜr CDK2/Cyclin E, CDK2/Cyclin A, CDK9/Cyclin T, CDK5/p25 und CDK1/Cyclin B bzw. (S)-CR8 reduziert das Überleben von SH-SY5Y-Zellen (IC50 0,40 μM). | ||||
| GC46379 | 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) | 90693-88-2 | >98.00% | |
1,2-Dioleoyl-sn-glycero-3-PS (Natriumsalz) ist ein Ersatzstoff fÜr Phosphoserin/Phosphatidylserin. | ||||
| GC46385 | 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose | 68733-20-0 | >95.00% | |
A ManNAc analog and building block | ||||
| GC46434 | 13C15-Nivalenol | 911392-40-0 | >98.00% | |
An internal standard for the quantification of nivalenol | ||||
| GC46446 | 15-deoxy-δ12,14-Prostaglandin J2-biotin | - | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46582 | 3-Acetyldeoxy Nivalenol-13C17 | 1217476-81-7 | >98.00% | |
An internal standard for the quantification of 3-acetyldeoxy nivalenol | ||||
| GC46606 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline | 214360-73-3 | >98.00% | |
A heterocyclic building block | ||||
| GC46635 | 4-deoxy Nivalenol-13C15 | 911392-36-4 | >98.00% | |
An internal standard for the quantification of 4-deoxy nivalenol | ||||
| GC46681 | 5-Bromouridine | 957-75-5 | >98.00% | |
A brominated uridine analog | ||||
| GC46687 | 5'-Deoxy-5'-methylthioadenosine-d3 | 174838-38-1 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46721 | 6-Chloro-2-fluoropurine | 1651-29-2 | >98.00% | |
A heterocyclic building block | ||||
| GC46733 | 7,12-Dimethylbenz[a]anthracene | 57-97-6 | >98.00% | |
7,12-Dimethylbenz[a]anthracen hat als polyzyklischer aromatischer Kohlenwasserstoff (PAK) krebserzeugende Wirkung. 7,12-Dimethylbenz[a]anthracen wird verwendet, um die Tumorbildung in verschiedenen Nagetiermodellen zu induzieren. | ||||
| GC46786 | Acetyl Hexapeptide-3 (acetate) | - | >95.00% | |
A synthetic hexapeptide | ||||
| GC46790 | Acibenzolar-S-methyl | 135158-54-2 | >99.00% | |
A fungicide inducer of systemic acquired resistance | ||||
| GC46791 | Ac-LEHD-pNA (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46796 | Ac-WEHD-AFC (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46810 | Aflatoxin B1-13C17 | 1217449-45-0 | >98.00% | |
An internal standard for the quantification of aflatoxin B 1 | ||||
| GC46811 | Aflatoxin B2-13C17 | 1217470-98-8 | >98.00% | |
An internal standard for the quantification of aflatoxin B 2 | ||||
| GC46814 | Aflatoxin M1-13C17 | 2707441-97-0 | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46825 | Alachlor | 15972-60-8 | >95.00% | |
An herbicide | ||||
| GC46841 | Amiloride (hydrochloride) (hydrate) | - | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46867 | Apremilast-d5 | 1258597-47-5 | >99.00% | |
Apremilast D5 (CC-10004 D5) ist ein Deuterium mit der Bezeichnung Apremilast. | ||||
| GC46878 | Aranciamycin | 72389-06-1 | >70.00% | |
A fungal metabolite with diverse biological activities | ||||