3,6-Dihydroxyflavone |
| Catalog No.GC64762 |
La 3,6-dihydroxyflavone est un agent anticancéreux. La 3,6-dihydroxyflavone diminue en fonction de la dose et du temps la viabilité cellulaire et induit l'apoptose en activant la cascade de caspases, en clivant la poly (ADP-ribose) polymérase (PARP). La 3,6-dihydroxyflavone augmente le stress oxydatif intracellulaire et la peroxydation lipidique.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 108238-41-1
Sample solution is provided at 25 µL, 10mM.
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3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].
[1]. Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38.
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