4-Thiouridine (Synonyms: NSC 518132, 4-SU) |
Catalog No.GC42474 |
La 4-thiouridine est un analogue de ribonucléoside, elle est largement utilisée dans l'analyse de l'ARN et le marquage (m)ARN.
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Cas No.: 13957-31-8
Sample solution is provided at 25 µL, 10mM.
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.
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