AGI-24512 |
| Catalog No.GC33019 |
AGI-24512 est un puissant inhibiteur de la méthionine adénosyltransférase 2α (MAT2A), avec une IC50 de 8 nM. AGI-24512 déclenche une réponse aux dommages À l'ADN. AGI-24512 peut bloquer la prolifération des cellules cancéreuses supprimées par MTAP in vitro. AGI-24512 peut être utilisé pour la recherche anticancéreuse.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2201066-53-5
Sample solution is provided at 25 µL, 10mM.
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AGI-24512 is a methionine adenosyltransferase 2A (MATA2 ) inhibitors useful for treatment of cancer. AGI-24512 blocks growth of MTAP-deleted cancer cells in vitro.
[1]. Agios. Targeting MAT2A in MTAP-deleted Cancers. Presented at the American Association for Cancer Research (AACR) Annual Meeting, April 14-18, 2018, Chicago, IL, USA
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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