Ald-CH2-PEG3-azide |
| Catalog No.GC66827 |
Ald-CH2-PEG3-azide est un linker PEG ADC clivable à 3 unités utilisé dans la synthèse de conjugués anticorps-médicament (ADC). Ald-CH2-PEG3-azide est un lieur PROTAC à base de PEG qui peut être utilisé dans la synthèse des PROTAC.
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Cas No.: 1002342-83-7
Sample solution is provided at 25 µL, 10mM.
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Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Harold L. Kohn , et al. Acylhydrazone-based cleavable linkers. WO2010014236A2.
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