Alendronic acid |
| Catalog No.GC39476 |
L'acide alendronique, un bisphosphonate, est un inhibiteur de la farnésyl diphosphate synthase (FDPS). L'acide alendronique inhibe la résorption osseuse médiée par les ostéoclastes. L'acide alendronique montre une efficacité dans l'ostéoporose post-ménopausique, l'hypercalcémie maligne et la maladie de Paget.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66376-36-1
Sample solution is provided at 25 µL, 10mM.
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Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget's disease[1].
[1]. Teixeira S, et al. Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma. Pharmaceutics. 2020 Mar 24;12(3). pii: E293. [2]. Duckworth AD, et al. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial. J Bone Miner Res. 2019 Jun;34(6):1025-1032.
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