Amprenavir-d4 (Synonyms: APV-d4, Prozei-d4) |
| Catalog No.GC45766 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Amprenavir-d4 is intended for use as an internal standard for the quantification of amprenavir by GC- or LC-MS. Amprenavir is an inhibitor of HIV protease (Ki = 0.04 nM).1 It inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 = 150 nM). Formulations containing amprenavir have been used in combination with other antiretroviral agents in the treatment of HIV-1 infection.
|1. Sherrill, R.G., Furfine, E.S., Hazen, R.J., et al. Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors. Bioorganic & Medicinal Chemistry Letters 15(15), 3560-3564 (2005).
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