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AMXT-1501

Catalog No.GC70563 Copy One-Click Copy Product Info

AMXT-1501 est un nouvel inhibiteur du système de transport des Polyamines.

Products are for research use only. Not for human use. We do not sell to patients.

AMXT-1501 Chemical Structure

Cas No.: 441022-64-6

Taille Prix Stock Qté
1 mg
180,00 $US
En stock
5 mg
495,00 $US
En stock
10 mg
765,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com


Avis des clients

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of AMXT-1501

AMXT1501 is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.

References:
[1]. Hayes CS, et al. Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. Cancer Immunol Res. 2014 Mar;2(3):274-85.

Chemical Properties of AMXT-1501

Cas No. 441022-64-6 SDF
Formula C32H68N6O2 M.Wt 568.92
Solubility Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of AMXT-1501

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7577 mL 8.7886 mL 17.5772 mL
5 mM 351.5 μL 1.7577 mL 3.5154 mL
10 mM 175.8 μL 878.9 μL 1.7577 mL
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In vivo Formulation Calculator (Clear solution) of AMXT-1501

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Avis

Review for AMXT-1501

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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