BTD |
| Catalog No.GC50617 |
Selective TRPC5 activator
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 896684-04-1
Sample solution is provided at 25 µL, 10mM.
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Selective TRPC5 activator (EC50 = 1.4 μM in a calcium influx assay, 1.3 μM in whole cell patch clamp assay). Displays >14.5-fold selectivity for TRPC5 over other TRP channels (EC50 = 20.6 μM for TRPM8). Also activates TRPC1:5 and TRPC4:5 heteromers.
Beckmann et al (2017) A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Cell Calcium. 66 10 PMID:28807145
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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