FIDAS-5 |
| Catalog No.GC39487 |
FIDAS-5 est un inhibiteur puissant et actif par voie orale de la méthionine S-adénosyltransférase 2A (MAT2A) avec une IC50 de 2,1 μM. FIDAS-5 entre efficacement en compétition avec la S-adénosylméthionine (SAM) pour la liaison de MAT2A. FIDAS-5 a des activités anticancéreuses.
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Cas No.: 1391934-98-7
Sample solution is provided at 25 µL, 10mM.
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FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1].
[1]. Zhang W, et al. Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8(4):796-803.
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