12(S)-HETE-d8 (Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid-d8) |
Catalog No.GC46414 |
12(S)-HETE-d8 contient huit atomes de deutérium aux positions 5, 6, 8, 9, 11, 12, 14 et 15. Le 12(S)-HETE-d8 est destiné À être utilisé comme étalon interne pour la quantification du 12(S)-HETE par spectrométrie de masse (MS) GC ou LC. 12(S)-HETE-d8 est le produit lipoxygénase prédominant des plaquettes de mammifères. Il améliore l'adhésion des cellules tumorales aux cellules endothéliales, À la fibronectine et À la matrice sous-endothéliale À 0,1 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 84807-90-9
Sample solution is provided at 25 µL, 10mM.
12(S)-
1.Hamberg, M., and Samuelsson, B.Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human plateletsProc. Natl. Acad. Sci. U.S.A.71(9)3400-3404(1974) 2.Grossi, I.M., Fitzgerald, L.A., Umbarger, L.A., et al.Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acidCancer Res.49(4)1029-1037(1989) 3.Honn, K.V., Nelson, K.K., Renaud, C., et al.Fatty acid modulation of tumor cell adhesion to microvessel endothelium and experimental metastasisProstaglandins44(5)413-429(1992)
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