Accueil>>Analytical Standards>>Arachidonoyl Ethanolamide-d8

Arachidonoyl Ethanolamide-d8 (Synonyms: AEAd8, Anandamided8)

Catalog No.GC46876

An internal standard for the quantification of arachidonoyl ethanolamide

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Arachidonoyl Ethanolamide-d8 Chemical Structure

Cas No.: 924894-98-4

Taille Prix Stock Qté
100 μg
66,00 $US
En stock
500 μg
294,00 $US
En stock
1 mg
521,00 $US
En stock
5 mg
2 278,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Arachidonoyl ethanolamide-d8 (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.1 It is an endogenous cannabinoid neurotransmitter that binds to both CB1 and CB2 receptors.2 AEA inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM, compared to 46 nM for δ9-THC.1

1.Devane, W.A., Hanus, L., Breuer, A., et al.Isolation and structure of a brain constituent that binds to the cannabinoid receptorScience258(5090)1946-1949(1992) 2.Felder, C.C., Briley, E.M., Axelrod, J., et al.Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transductionProc. Natl. Acad. Sci. U.S.A.90(16)7656-7660(1993)

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