Burnettramic Acid A aglycone |
| Catalog No.GC48409 |
Acide burnettramique Un aglycone est un métabolite fongique présent dans Aspergillus burnettii.
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Cas No.: 2396676-46-1
Sample solution is provided at 25 µL, 10mM.
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Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated from A. burnettii that has anticancer activity.1 It is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 8.4 and >100 µg/ml, respectively).
1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)
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