PAR4 (1-6) (mouse) (trifluoroacetate salt) (Synonyms: GYPGKF, H-Gly-Tyr-Pro-Gly-Lys-Phe-OH) |
| Catalog No.GC40156 |
PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4; EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence.
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Sample solution is provided at 25 µL, 10mM.
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PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4; EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence. It induces calcium release in wild-type and PAR3-/- mouse platelets and in human platelets but has no activity in Xenopus oocytes expressing human PAR1. PAR4 (1-6) also triggers [3H]inositol phosphate release from KOLF cells expressing human PAR4.
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