Accueil>>Labeling & Detection>> Cyanine Dyes>>Cy5 amine (non-sulfonated)

Cy5 amine (non-sulfonated) (Synonyms: Cyanine5 amine)

Catalog No.GC14394

can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

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Cy5 amine (non-sulfonated) Chemical Structure

Taille Prix Stock Qté
1mg
154,00 $US
En stock
5mg
294,00 $US
En stock
25mg
574,00 $US
En stock
50mg
973,00 $US
En stock
100mg
1 666,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cy5 amine is a reactive dye which contains amino group. This dye can be coupled with a variety of activated esters and other electrophilic reagents. For instance, this amine can be coupled with EDC-activated carboxylic groups. With this bright and photostable reagent, many different methods of fluorescence detection is available and colorful fluorophore can also be easily detected in small quantities by naked human eye. For biomolecule labeling, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.

In A2780 cells, the conjugates polymer 2P-Cy3-Cy5 can be used for the analysis of the pair-correlation functions between Cy3 and Cy5. Treated with 2P-Cy3-Cy5 for several hours show similar shape and characteristic decay lengths [1].

Reference:
[1]Hartley, J. M.; Zhang, R.; Gudheti, M.; Yang, J.; Kopeek, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59.

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