Doxorubicin-SMCC |
| Catalog No.GC62134 |
La doxorubicine-SMCC est un conjugué médicament-lieur pour l'ADC. La doxorubicine-SMCC contient un lieur ADC non clivable et un inhibiteur de l'ADN topoisomérase II, la doxorubicine.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 400647-59-8
Sample solution is provided at 25 µL, 10mM.
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Doxorubicin-SMCC is a drug-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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