Finafloxacin |
| Catalog No.GC33917 |
La finafloxacine est un agent antimicrobien fluoroquinolone qui présente une efficacité optimale dans des environnements légèrement acides.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 209342-40-5
Sample solution is provided at 25 µL, 10mM.
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Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Target: AntibacterialFinafloxacin is a pH-activated fluoroquinolone (belonging to a new 8-cyano subclass) to treat serious bacterial infections associated with an acidic environment, including urinary tract infections (UTIs) and Helicobacter pylori infections. Finafloxacin exhibits optimal efficacy in slightly acidic environments (pH 5.0-6.0), under which other fluoroquinolones lose activity. Finafloxacin is highly selective for bacterial type II topoisomerases, including DNA gyrase and DNA topoisomerase IV. [1]
[1]. McKeage K. Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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