FOXO4-DRI |
Catalog No.GC26231 |
FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2460055-10-9
Sample solution is provided at 25 µL, 10mM.
FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI is a senolytic peptide that induces apoptosis of senescent cells[1].
References:
[1]. Zhang C, et al. FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Aging (Albany NY). 2020 Jan 20;12(2):1272-1284.
[2]. Huang Y, et al. Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes. Front Bioeng Biotechnol. 2021 Apr 29;9:677576.
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